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OCR: Peter H. Sonksen MD, FRCP Professor of Endocrinology Chairman, Division of Endocrinology and Chemical Pathology United Medical and Dental Schools of Guy's and St. Thomas's Hospitals St. Thomas's Hospital, London, UK Dennis M. Styne MD Professor and Chair, Department of Paediatrics University of California, Davis Medical Centre Sacramento, California, USA Tony E. Torresani PhD Biochemist, Chief of Protein Hormone Laboratory Children's Hospital Department of Endocrinology University of Zurich Zurich, Switzerland